It is time to speed up the process for approving low risk organic pesticides (micro-organisms, plants, chemicals or semichemical bioderivate as pheromones and essential oils).
It was asked by members of the European Parliament in a resolution voted in mid-February:
– They ask why some Member States are reluctant or refuse approval
– They invite the European Commission to propose a revision of the rules for approval by the end of 2018 by introducing an accelerated procedure for the evaluation, authorization and registration of low-risk pesticides.
At the moment, only seven active substances are authorized classified as “low risk” pesticides.
Meanwhile, many researches were produced to evaluate the potential risks.
This is the case of secondary metabolites produced by fungi used as biopesticides.
Microbial metabolites may pose a risk to humans, animals and the environment. Therefore, it is critical to know whether a particular strain of a fungus produces potentially harmful metabolites.
An in-depth study was carried out by the European project RAFBCA (Risk Assessment of Fungal BioControl Agents) that examined and evaluated the simplest methods that could be developed to assess the potential risks of metabolites (the effects of the crude extracts were compared with those of purified metabolites).
In particular, RAFBCA assessed whether the metabolites produced by fungal biological control agents enter the food chain and if they constitute a risk to human and animal health by:
– Development of tools (eg. Biosensors) and methods (eg. High-performance test as ELISA, Vito ox) for quick and accurate detection of fungal metabolites,
– Biochemical and molecular studies to clarify their mode of action,
– Molecular markers to monitor fungal metabolites in the environment,
– Studies to determine whether the metabolites enter the food chain.
The RAFBCA team identified strains based on Beauveria brongniartii, Metarhizium anisopliae, Verticillium lecanii), mycofungicide (Gliocladium spp., Trichoderma harzianum) and mycoerbicide (Stagonospora convolvuli) and the major metabolites (oosporein, destruxins, gliotoxin, peptaibols, elsinochrome A).
Another issue is the discrepancy between the analytical data required from different countries. One proposal to overcome this situation came from the OECD Committee on biopesticides that started the development of a guidance document on metabolites.
Renolab has a long and deep experience of studies in Good Laboratory Practices on pheromones. It conducts analysis of the 5-batch on technical substance, it search for impurities, it carry out complete physical-chemical studies on active ingredients and formulated. Upon request it performs analysis to achieve release curves. Contact us for information or to request a quote.